Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044565 | 0.95 | HSD17B10 (0.57) | HSD17B10AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL4318333 | 0.81 | HSD17B10 (0.69) | HSD17B10AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL9174491 | 0.80 | HSD17B10 (0.43) | HSD17B10AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL7813490 | 0.77 | HSD17B10 (1.00) | HSD17B10AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL8374273 | 0.75 | HSD17B10 (0.39) | HSD17B10AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL9173276 | 0.75 | HTT (0.47) | HSD17B10KDM4EMEN1LMNAHTT | |
| SCHEMBL8372308 | 0.74 | HSD17B10 (0.59) | HSD17B10AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL8541393 | 0.72 | HSD17B10 (0.67) | HSD17B10AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL8056715 | 0.72 | HSD17B10 (0.67) | HSD17B10AKR1C3AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL8372180 | 0.70 | POLB (0.35) | HSD17B10KDM4ETPMTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669940-B1 | SPECIFICALLY CROSSLINKED HEMOGLOBIN WITH FREE FUNCTIONALITY | UNIV TORONTO (CA) | 1999-02-10 | — | — | EP | claimed |
| US-11298407-B2 | Hemoglobin based oxygen carrier and method of preparation | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2022-04-12 | — | — | US | disclosed |
| WO-2018053634-A1 | HEMOGLOBIN BASED OXYGEN CARRIER AND METHOD OF PREPARATION | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2018-03-29 | — | — | WO | disclosed |
| WO-2017197499-A1 | STABILIZED HEMOGLOBIN-AVIDIN ASSEMBLY AND METHOD OF PREPARATION | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2017-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11298407-B2 | Hemoglobin based oxygen carrier and method of preparation | HBZ, HBB, HBG2 | HSD17B10 2382/4885AKR1C3 867/4885AKR1C2 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.