Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9174756 | 1.00 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1PTPRCPTPN1PTGER1 | |
| SCHEMBL8629212 | 0.83 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1PTPRCPTPN1 | |
| SCHEMBL8629215 | 0.83 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1PTPRCPTPN1 | |
| SCHEMBL13950635 | 0.79 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1PTGER1PTGER4PTGER3 | |
| SCHEMBL9170805 | 0.79 | CYSLTR1 (0.43) | CYSLTR1 | |
| SCHEMBL692870 | 0.78 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1PTGER1PTGER4PTGER3 | |
| SCHEMBL692871 | 0.78 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1PTGER1PTGER4PTGER3 | |
| SCHEMBL13983960 | 0.77 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1PTGER1PTGER4PTGER3 | |
| SCHEMBL8496429 | 0.76 | CYSLTR1 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL8496432 | 0.76 | CYSLTR1 (0.49) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438141-A | Antiasthmatic agents, antiallergens | MERCK FROSST CANADA, INC. (CA) | 1995-08-01 | — | — | US | disclosed |
| WO-1994027968-A1 | QUINOLINE DERIVATIVES AS LEUKOTRIENE ANTAGONISTS | MERCK FROSST CANADA INC. (CA) | 1994-12-08 | — | — | WO | disclosed |