SCHEMBL9176012

COc1ccc(C(c2ccccc2)(c2ccc(OC)cc2)C(O)[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)[C@H](O)[C@@]2(O)S(C)(=O)=O)cc1

nearest known ligand 0.40

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY14	Q15391	4/20	0.40

▸	NT5E	P21589	1/20	0.37

▸	P2RY2	P41231	5/20	0.36

▸	P2RY6	Q15077	4/20	0.36

▸	SLC28A1	O00337	1/20	0.36

▸	SLC28A2	O43868	1/20	0.36

▸	SLC29A1	Q99808	1/20	0.36

▸	SLC28A3	Q9HAS3	1/20	0.36

▸	DUT	P33316	2/20	0.35

▸	TYMP	P19971	1/20	0.34

▸	P2RY4	P51582	2/20	0.34

▸	P2RY12	Q9H244	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9176009	0.89	NT5E (0.38)	P2RY14NT5EP2RY2P2RY6SLC28A1
SCHEMBL9174054	0.84	P2RY14 (0.35)	P2RY14NT5EP2RY2P2RY6SLC28A1
SCHEMBL8970004	0.81	P2RY14 (0.39)	P2RY14NT5EP2RY2P2RY6SLC28A1
SCHEMBL10336769	0.81	NT5E (0.47)	P2RY14NT5EP2RY2P2RY6SLC28A1
SCHEMBL442715	0.81	P2RY14 (0.48)	P2RY14P2RY2P2RY6SLC28A1SLC28A2
SCHEMBL443536	0.78	DUT (0.34)	P2RY14DUT
SCHEMBL6832098	0.78	P2RY14 (0.44)	P2RY14P2RY2P2RY6SLC28A1SLC28A2
SCHEMBL8538694	0.78	P2RY14 (0.44)	P2RY14P2RY2P2RY6SLC28A1SLC28A2
SCHEMBL8210384	0.78	P2RY14 (0.44)	P2RY14P2RY2P2RY6SLC28A1SLC28A2
SCHEMBL8970268	0.78	P2RY14 (0.46)	P2RY14P2RY2P2RY6SLC28A1SLC28A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0365556-B1	NUCLEOSIDE ANALOGUES	GENENTECH INC (US)	1995-07-12	—	—	EP	disclosed