Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14229002 | 0.84 | ESR2 (0.52) | L3MBTL1KDM1ARCOR1EPHX2HRH3 | |
| SCHEMBL22209907 | 0.82 | L3MBTL1 (0.44) | L3MBTL1KDM1ARCOR1EPHX2HRH3 | |
| SCHEMBL19733791 | 0.81 | L3MBTL1 (0.43) | L3MBTL1KDM1ARCOR1EPHX2HRH3 | |
| SCHEMBL4564168 | 0.80 | L3MBTL1 (0.47) | L3MBTL1KDM1ARCOR1EPHX2HRH3 | |
| Hydrochloric Acid SCHEMBL21491485 | 0.80 | KDM1A (0.48) | L3MBTL1KDM1ARCOR1EPHX2HRH3 | |
| SCHEMBL9979949 | 0.80 | ESR2 (0.47) | L3MBTL1KDM1ARCOR1EPHX2HRH3 | |
| SCHEMBL8728119 | 0.80 | KDM1A (0.48) | L3MBTL1KDM1ARCOR1EPHX2HRH3 | |
| SCHEMBL15180918 | 0.80 | L3MBTL1 (0.48) | L3MBTL1KDM1ARCOR1EPHX2HRH3 | |
| SCHEMBL12875677 | 0.79 | KDM1A (0.47) | L3MBTL1KDM1ARCOR1EPHX2ALDH1A1 | |
| SCHEMBL18998726 | 0.79 | KDM1A (0.47) | L3MBTL1KDM1ARCOR1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5445764-A | Based on derivatives of m-difluorobenzene; low viscosity; stability; broad mesophase range; good optical and dielectric anisotropy; specific resistance; matrix and supertwist displays | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0623102-A1 | CYCLOBUTANE-BENZOLE DERIVATIVES | MERCK PATENT GmbH (DE) | 1994-11-09 | — | — | EP | disclosed |
| WO-1994012455-A1 | CYCLOBUTANE-BENZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 1994-06-09 | — | — | WO | disclosed |