Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IL18 | Q14116 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198208 | 0.86 | ALOX5 (0.61) | ALOX5ACACBACACAMEN1LMNA | |
| SCHEMBL9175836 | 0.78 | ALOX5 (0.69) | ALOX5ACACBACACASCN9AKDM4E | |
| SCHEMBL10927383 | 0.73 | CYP19A1 (0.59) | SCN9ACYP19A1KDM4EMEN1LMNA | |
| SCHEMBL10923033 | 0.73 | PDE4A (0.55) | SCN9ACYP19A1MEN1MAPTKMT2A | |
| SCHEMBL9171356 | 0.73 | MAPT (0.47) | ALOX5SCN9ACYP19A1KDM4EMEN1 | |
| SCHEMBL7073983 | 0.72 | CYP19A1 (0.54) | CYP19A1KDM4EMEN1LMNAPOLB | |
| SCHEMBL15472272 | 0.72 | MAPT (0.50) | ALOX5SCN9ACYP19A1MEN1MAPT | |
| SCHEMBL9352092 | 0.72 | ALOX5 (0.61) | ALOX5ACACBKDM4EMEN1LMNA | |
| SCHEMBL507026 | 0.72 | CYP19A1 (0.47) | ALOX5SCN9ACYP19A1KDM4EMEN1 | |
| SCHEMBL8203531 | 0.71 | ALOX5 (0.67) | ALOX5ACACBACACASCN9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652864-A1 | HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994002448-A1 | HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-02-03 | — | — | WO | disclosed |