Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18789268 | 0.91 | GFER (0.65) | GFERMAOBMAOALOXL2ALDH1A1 | |
| SCHEMBL7211656 | 0.81 | DRD2 (0.55) | GFERCYP3A4TSHRKDM4EMAPT | |
| SCHEMBL9768688 | 0.80 | TAAR1 (0.58) | MAOALOXL2TDP1TAAR1CYP1A2 | |
| SCHEMBL9125321 | 0.80 | MAPT (0.62) | GFERMAOBMAOALOXL2ALDH1A1 | |
| SCHEMBL13937396 | 0.80 | TAAR1 (0.58) | MAOALOXL2TDP1TAAR1CYP1A2 | |
| SCHEMBL9630022 | 0.78 | GFER (0.54) | GFERMAOBMAOAALDH1A1CYP3A4 | |
| SCHEMBL13937401 | 0.78 | TAAR1 (0.56) | MAOALOXL2TAAR1CYP1A2CYP2A6 | |
| SCHEMBL3161700 | 0.78 | GFER (0.54) | GFERMAOBMAOAALDH1A1CYP3A4 | |
| SCHEMBL143553 | 0.78 | GFER (0.77) | GFERMAOBMAOALOXL2ALDH1A1 | |
| SCHEMBL10618368 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHRSIGMAR1TAAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653941-A1 | TARGETED DELIVERY OF GROWTH FACTORS FOR BONE REGENERATION | THE DOW CHEMICAL COMPANY (US) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994000145-A1 | TARGETED DELIVERY OF GROWTH FACTORS FOR BONE REGENERATION | THE DOW CHEMICAL COMPANY (US) | 1994-01-06 | — | — | WO | disclosed |