Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | CA2 | P00918 | 8/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10578855 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CA2TSHRCYP3A4TDP1 | |
| SCHEMBL38661702 | 0.92 | ALDH1A1 (0.48) | ALDH1A1CA2TSHRCYP3A4TDP1 | |
| SCHEMBL10609026 | 0.86 | TSHR (0.40) | ALDH1A1CA2TSHRCYP3A4TDP1 | |
| SCHEMBL10609028 | 0.86 | TSHR (0.40) | ALDH1A1CA2TSHRCYP3A4TDP1 | |
| SCHEMBL10609023 | 0.86 | TSHR (0.40) | ALDH1A1CA2TSHRCYP3A4TDP1 | |
| SCHEMBL20232280 | 0.85 | ALDH1A1 (0.43) | ALDH1A1CA2TSHRCYP3A4TDP1 | |
| SCHEMBL31065656 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CA2TSHRTP53 | |
| SCHEMBL31065655 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CA2TSHRTP53 | |
| SCHEMBL34462660 | 0.84 | ALDH1A1 (0.48) | ALDH1A1CA2TSHRTP53CA1 | |
| SCHEMBL21881977 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CA2TSHRCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420347-A | Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-glycyl-D-alanine | PFIZER INC. (US) | 1995-05-30 | — | — | US | disclosed |
| US-5286904-A | Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-glycyl-D-alanine | PFIZER INC. (US) | 1994-02-15 | — | — | US | disclosed |
| US-5245079-A | Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-glycyl-D-alanine | PFIZER INC. (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0258032-B1 | PROCESSES AND INTERMEDIATES FOR N-(S-3-ALKYLHEPTANOYL)-D-GAMMA-GLUTAMYL-GLYCYL-D-ALANINE | PFIZER INC. (US) | 1992-07-29 | — | — | EP | disclosed |
| US-5134225-A | Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-D-alanine | PFIZER INC. (US) | 1992-07-28 | — | — | US | disclosed |
| WO-1988001612-A1 | PROCESSES AND INTERMEDIATES FOR N-(S-3-ALKYL-HEPTANOYL)-D-GAMMA-GLUTAMYL-GLYCYL-D-ALANINE | PFIZER INC. (US) | 1988-03-10 | — | — | WO | disclosed |
| EP-0258032-A2 | Processes and intermediates for N-(S-3-alkylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine | PFIZER INC. (US) | 1988-03-02 | — | — | EP | disclosed |