Thiodiglycol

Thiodiglycol

SCHEMBL9177341

CCCCCCCCCCCCCCCCCCOCCCCCCCCCCCCCCCCCC.OCCSCCO

nearest known ligand 0.66

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
HTT P42858 2/20 0.65
THRB P10828 1/20 0.65
MAPT P10636 1/20 0.65
TSHR P16473 2/20 0.54
USP2 O75604 1/20 0.47
CES2 O00748 2/20 0.45
LMNA P02545 2/20 0.44
ALDH1A1 P00352 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
CES1 P23141 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
PLA2G4B P0C869 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9696034 0.96 MEN1 (0.61) MEN1KMT2AHTTTHRBMAPT
SCHEMBL9695341 0.96 MEN1 (0.61) MEN1KMT2AHTTTHRBMAPT
SCHEMBL11079372 0.88 MEN1 (0.61) MEN1KMT2AHTTTHRBMAPT
SCHEMBL11086153 0.88 MEN1 (0.61) MEN1KMT2AHTTTHRBMAPT
SCHEMBL11081399 0.88 MEN1 (0.61) MEN1KMT2AHTTTHRBMAPT
SCHEMBL11080723 0.88 MEN1 (0.61) MEN1KMT2AHTTTHRBMAPT
SCHEMBL11077154 0.88 MEN1 (0.61) MEN1KMT2AHTTTHRBMAPT
SCHEMBL4016728 0.87 TSHR (0.60) MEN1KMT2AHTTTHRBMAPT
SCHEMBL11081916 0.86 MEN1 (0.59) MEN1KMT2AHTTTHRBMAPT
SCHEMBL6694682 0.84 HTT (0.54) MEN1KMT2AHTTTHRBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5470493-A Process for softening fabrics by contacting them with a thiodiglycol derivative HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1995-11-28 US disclosed