Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695341 | 1.00 | MEN1 (0.61) | MEN1KMT2AHTTTHRBMAPT | |
| Thiodiglycol SCHEMBL9177341 | 0.96 | MEN1 (0.65) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL11081916 | 0.90 | MEN1 (0.59) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL6694682 | 0.89 | HTT (0.54) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL7637734 | 0.89 | HTT (0.54) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL10931986 | 0.86 | MEN1 (0.53) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL11086847 | 0.86 | TSHR (0.54) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL11282019 | 0.85 | TDP1 (0.46) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL11086153 | 0.84 | MEN1 (0.61) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL11080723 | 0.84 | MEN1 (0.61) | MEN1KMT2AHTTTHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134151-A | Platelet Activating Factor Antagonist | J. URIACH & CIA (ES) | 1992-07-28 | — | — | US | disclosed |
| EP-0385490-A1 | 2-picolylamine derivates | J. URIACH & CIA. S.A. (ES) | 1990-09-05 | — | — | EP | disclosed |