Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637734 | 1.00 | HTT (0.54) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL29462498 | 0.91 | THRB (0.45) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL29462497 | 0.90 | CES2 (0.45) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL14809996 | 0.90 | THRB (0.54) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL7602668 | 0.90 | CES2 (0.45) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL14809573 | 0.90 | THRB (0.54) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL5382481 | 0.90 | CES2 (0.45) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL9696034 | 0.89 | MEN1 (0.61) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL9695341 | 0.89 | MEN1 (0.61) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL10693368 | 0.88 | THRB (0.58) | HTTTHRBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987295-B1 | Combination of an organothio compound and a zinc mercapto ester as heat stabilizer in PVC processing | MORTON INT INC (US) | 2004-07-21 | — | — | EP | disclosed |
| US-6462116-B2 | POLYVINYL CHLORIDE(PVC), OR OTHER HALOPOLYMERS; 2-MERCAPTOETHANOL AND ZINC BIS(2-ETHYLHEXYLTHIOGLYCOLATE) FOR EXAMPLE; ELIMINATES ZINC BURN DURING PROCESSING | MORTON INTERNATIONAL, INC. | 2002-10-08 | — | — | US | disclosed |
| US-20010036987-A1 | Combination of an organothio compound and a zinc mercapto ester as a heat stabilizer in PVC processing | MORTON INTERNATIONAL, INC. | 2001-11-01 | — | — | US | disclosed |
| EP-0987295-A1 | Combination of an organothio compound and a zinc mercapto ester as heat stabilizer in PVC processing | MORTON INTERNATIONAL, INC. (US) | 2000-03-22 | — | — | EP | disclosed |