Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31577617 | 0.87 | OPRM1 (0.53) | TRPM8TRPA1OPRM1EPHX1KCNA5 | |
| SCHEMBL31546067 | 0.80 | OPRM1 (0.58) | TRPM8TRPA1OPRM1EPHX1KCNA5 | |
| SCHEMBL24513787 | 0.79 | OPRM1 (0.64) | TRPM8TRPA1OPRM1EPHX1KCNA5 | |
| SCHEMBL22430737 | 0.79 | OPRM1 (0.64) | TRPM8TRPA1OPRM1EPHX1KCNA5 | |
| SCHEMBL10594114 | 0.79 | OPRM1 (0.64) | TRPM8TRPA1OPRM1EPHX1KCNA5 | |
| SCHEMBL22430812 | 0.79 | OPRM1 (0.64) | TRPM8TRPA1OPRM1EPHX1KCNA5 | |
| SCHEMBL11729019 | 0.78 | TRPM8 (0.46) | TRPM8TRPA1OPRM1EPHX1KCNA5 | |
| SCHEMBL10700915 | 0.78 | KCNA5 (0.50) | TRPM8TRPA1OPRM1EPHX1KCNA5 | |
| SCHEMBL10715246 | 0.77 | TRPM8 (0.44) | TRPM8TRPA1OPRM1EPHX1KCNA5 | |
| SCHEMBL3639819 | 0.77 | KCNA5 (0.53) | TRPM8TRPA1OPRM1KCNA5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407879-B1 | Method for mutli-dimensional measurement of magnetic resonance in defined small volume regions of a solid-state sample | BRUKER MEDIZINTECH (DE) | 1995-07-05 | — | — | EP | disclosed |
| EP-0407879-A2 | Method for mutli-dimensional measurement of magnetic resonance in defined small volume regions of a solid-state sample | Bruker Medizintechnik GmbH (DE) | 1991-01-16 | — | — | EP | disclosed |