Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183387 | 1.00 | PTGS2 (0.41) | PTGS2ESR1ESR2CYP3A4CYP1A2 | |
| SCHEMBL9183797 | 1.00 | PTGS2 (0.41) | PTGS2ESR1ESR2CYP3A4CYP1A2 | |
| SCHEMBL9184040 | 1.00 | PTGS2 (0.41) | PTGS2ESR1ESR2CYP3A4CYP1A2 | |
| SCHEMBL9180719 | 1.00 | PTGS2 (0.41) | PTGS2ESR1ESR2CYP3A4CYP1A2 | |
| SCHEMBL9184232 | 1.00 | PTGS2 (0.41) | PTGS2ESR1ESR2CYP3A4CYP1A2 | |
| SCHEMBL9185268 | 1.00 | PTGS2 (0.41) | PTGS2ESR1ESR2CYP3A4CYP1A2 | |
| SCHEMBL9180104 | 1.00 | PTGS2 (0.41) | PTGS2ESR1ESR2CYP3A4CYP1A2 | |
| SCHEMBL9176669 | 0.98 | ESR1 (0.40) | PTGS2ESR1ESR2CYP3A4CYP1A2 | |
| SCHEMBL2914501 | 0.90 | TNKS2 (0.41) | PTGS2ESR1ESR2CYP3A4CYP1A2 | |
| SCHEMBL9575261 | 0.89 | ESR1 (0.36) | PTGS2ESR1ESR2CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5473003-A | A styrene copolymer blend comprising a stabilizer for heat, oxidation, chemical and actinic radiation resistance | CIBA-GEIGY CORPORATION (US) | 1995-12-05 | — | — | US | disclosed |