Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9176669 | 0.91 | ESR1 (0.40) | ESR1ESR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8340801 | 0.91 | GAA (0.40) | ESR1ESR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9178100 | 0.89 | PTGS2 (0.41) | ESR1ESR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9184232 | 0.89 | PTGS2 (0.41) | ESR1ESR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9180104 | 0.89 | PTGS2 (0.41) | ESR1ESR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9185268 | 0.89 | PTGS2 (0.41) | ESR1ESR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9183387 | 0.89 | PTGS2 (0.41) | ESR1ESR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9180719 | 0.89 | PTGS2 (0.41) | ESR1ESR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9184040 | 0.89 | PTGS2 (0.41) | ESR1ESR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9183797 | 0.89 | PTGS2 (0.41) | ESR1ESR2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303280-B1 | PHENOLIC ANTIOXIDANT HYDRAZIDES | ATOCHEM NORTH AMERICA, INC. (US) | 1993-03-24 | — | — | EP | disclosed |
| EP-0303280-A2 | Phenolic antioxidant hydrazides | ATOCHEM NORTH AMERICA, INC. (US) | 1989-02-15 | — | — | EP | disclosed |
| US-4801749-A | Phenolic antioxidant hydrazides | PENNWALT CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |