Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959956 | 0.82 | ELANE (0.46) | ELANEACHECA2CYP3A4BCHE | |
| SCHEMBL8581995 | 0.82 | ELANE (0.49) | ELANEACHECYP3A4BCHEL3MBTL1 | |
| SCHEMBL8781783 | 0.81 | ELANE (0.60) | ELANECA2CYP3A4L3MBTL1ATM | |
| SCHEMBL10148455 | 0.80 | HDAC4 (0.46) | ELANEACHECA2BCHEFAAH | |
| SCHEMBL9174578 | 0.79 | BCHE (0.39) | ELANEACHEBCHEL3MBTL1ATM | |
| SCHEMBL16952675 | 0.78 | ELANE (0.51) | ELANEACHECA2CYP3A4BCHE | |
| SCHEMBL6392035 | 0.78 | CYP3A4 (0.62) | ELANECA2CYP3A4KDM1AESR1 | |
| SCHEMBL2738445 | 0.76 | LMNA (0.61) | ELANEACHECYP3A4BCHEFAAH | |
| SCHEMBL12315891 | 0.76 | ELANE (0.53) | ELANEACHECA2CYP3A4KDM1A | |
| SCHEMBL1792489 | 0.75 | ELANE (0.51) | ELANEACHECA2CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525626-B1 | Compounds containing acid-cleavable protective groups and positive-working radiation-sensitive compositions prepared using these compounds | HOECHST AG (DE) | 1995-06-14 | — | — | EP | disclosed |
| US-5356752-A | Compounds with acid-labile protective groups useful in positive-working radiation-sensitive mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-18 | — | — | US | disclosed |
| EP-0525626-A1 | Compounds containing acid-cleavable protective groups and positive-working radiation-sensitive compositions prepared using these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-03 | — | — | EP | disclosed |