Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819332 | 0.85 | LMNA (0.74) | LMNAMAPTMAPK1ALOX15HSD17B10 | |
| SCHEMBL29418226 | 0.85 | LMNA (0.74) | LMNAMAPTMAPK1ALOX15HSD17B10 | |
| SCHEMBL6392035 | 0.84 | CYP3A4 (0.62) | LMNAELANEPOLBALDH1A1KMT2A | |
| SCHEMBL12315891 | 0.83 | ELANE (0.53) | LMNAELANEACHEKMT2AMEN1 | |
| SCHEMBL16675180 | 0.82 | LMNA (0.69) | LMNAMAPTMAPK1ALOX15HSD17B10 | |
| SCHEMBL28240516 | 0.82 | ELANE (0.55) | LMNAELANEMAPTMAPK1ALDH1A1 | |
| SCHEMBL16952675 | 0.81 | ELANE (0.51) | LMNAELANEACHEKMT2ABCHE | |
| SCHEMBL1792489 | 0.81 | ELANE (0.51) | LMNAELANEACHEKMT2AMEN1 | |
| SCHEMBL6191776 | 0.81 | ELANE (0.51) | LMNAELANEMAPTPOLBALDH1A1 | |
| SCHEMBL1789018 | 0.81 | ELANE (0.51) | LMNAELANEALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365513-B2 | Fullerene derivative, and method of preparing the same | RICOH COMPANY, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9365513-B2 | Fullerene derivative, and method of preparing the same | RICOH COMPANY, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-20150158814-A1 | FULLERENE DERIVATIVE, AND METHOD OF PREPARING THE SAME | RICOH COMPANY, LTD. (JP) | 2015-06-11 | — | — | US | disclosed |
| US-20150158814-A1 | FULLERENE DERIVATIVE, AND METHOD OF PREPARING THE SAME | RICOH COMPANY, LTD. (JP) | 2015-06-11 | — | — | US | disclosed |
| US-8088554-B2 | Bottom resist layer composition and patterning process using the same | SHIN-ETSU CHEMICAL CO., LTD (JP) | 2012-01-03 | — | — | US | disclosed |
| US-8088554-B2 | Bottom resist layer composition and patterning process using the same | SHIN-ETSU CHEMICAL CO., LTD (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20100151382-A1 | Bottom resist layer composition and patterning process using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100151382-A1 | Bottom resist layer composition and patterning process using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-7183267-B2 | β-lactamase inhibitors and methods of use thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2007-02-27 | — | — | US | disclosed |
| US-7183267-B2 | β-lactamase inhibitors and methods of use thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2007-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158814-A1 | FULLERENE DERIVATIVE, AND METHOD OF PREPARING THE SAME | NCL, PFDN2, NUP50 | LMNA 1111/4885ELANE 1208/4885MAPT 1256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.