Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.66 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.31 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20109484 | 0.79 | NUDT1 (1.00) | NUDT1PDPK1TGFBR1 | |
| SCHEMBL1576638 | 0.76 | NUDT1 (0.65) | NUDT1PDPK1TGFBR1KMT2AMEN1 | |
| SCHEMBL9182270 | 0.75 | NUDT1 (0.66) | NUDT1PDPK1TGFBR1KMT2AHRH4 | |
| SCHEMBL7718036 | 0.75 | NUDT1 (0.66) | NUDT1PDPK1TGFBR1KMT2AMEN1 | |
| SCHEMBL17589006 | 0.74 | SMN1; SMN2 (0.46) | NUDT1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL1317216 | 0.74 | CYP2C19 (0.50) | KMT2AHRH4KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL20109486 | 0.72 | NUDT1 (0.62) | NUDT1PDPK1TGFBR1HRH4 | |
| SCHEMBL7164892 | 0.72 | NUDT1 (0.62) | NUDT1HRH4CYP2D6 | |
| SCHEMBL21016702 | 0.70 | JAK3 (0.38) | NUDT1L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL7522734 | 0.70 | TLR8 (0.65) | NUDT1HRH4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519819-B1 | Composition for use to reduce hair loss and to induce and stimulate its growth, containing derivatives of 2,4,6-triaminopyrimidin-N-oxide and the new derivatives of 2,4,6-triaminopyrimidin-N-oxide | OREAL (FR) | 1995-07-19 | — | — | EP | disclosed |
| EP-0519819-A1 | Composition for use to reduce hair loss and to induce and stimulate its growth, containing derivatives of 2,4,6-triaminopyrimidin-N-oxide and the new derivatives of 2,4,6-triaminopyrimidin-N-oxide | L'OREAL (FR) | 1992-12-23 | — | — | EP | disclosed |