Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.55 |
| ▸ | PPARG | P37231 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177249 | 0.89 | PPARA (0.61) | PPARAPPARGKDM4ETDP1HPGD | |
| SCHEMBL9177050 | 0.88 | PPARA (0.62) | PPARAPPARGMAPTTP53 | |
| SCHEMBL9262328 | 0.88 | KDM4E (0.55) | ALDH1A1KDM4ETDP1HPGDRAB9A | |
| SCHEMBL10520058 | 0.82 | RAB9A (0.55) | PPARAPPARGALDH1A1KDM4ETDP1 | |
| SCHEMBL9177913 | 0.80 | PPARA (0.59) | PPARAPPARGALDH1A1KDM4ETDP1 | |
| SCHEMBL9178370 | 0.79 | TDP1 (0.62) | PPARAPPARGALDH1A1KDM4ETDP1 | |
| SCHEMBL9179031 | 0.79 | KDM4E (0.48) | PPARAPPARGALDH1A1KDM4ETDP1 | |
| SCHEMBL9179028 | 0.79 | KDM4E (0.48) | PPARAPPARGALDH1A1KDM4ETDP1 | |
| SCHEMBL10519163 | 0.78 | TP53 (0.49) | PPARAPPARGALDH1A1KDM4ETDP1 | |
| SCHEMBL9257856 | 0.78 | ALDH1A1 (0.50) | PPARAALDH1A1KDM4EHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468760-A | Treating atherosclerosis, inflammation, and asthma | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |