Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PARK7 | Q99497 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470716 | 0.95 | CES1 (0.56) | CES1NPSR1ALDH1A1MAPTHTT | |
| SCHEMBL9170783 | 0.81 | CES1 (0.62) | CES1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL10367966 | 0.81 | CES1 (0.62) | CES1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL10367642 | 0.81 | CES1 (0.62) | CES1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL5363737 | 0.78 | CES1 (0.59) | CES1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL8768338 | 0.77 | CES1 (1.00) | CES1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL9172070 | 0.76 | CES1 (0.56) | CES1ALDH1A1MAPTHTTMEN1 | |
| SCHEMBL1762467 | 0.75 | CYP11B1 (0.54) | MEN1TSHRKMT2A | |
| SCHEMBL29876793 | 0.75 | NPC1 (0.57) | MAPTMEN1TSHRKMT2ANPC1 | |
| SCHEMBL9177549 | 0.73 | CES1 (0.39) | CES1MAPTPARK7TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310096-B1 | Novel cyclic anthranilic acid derivatives and process for their preparation | KYORIN SEIYAKU KK (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-5147874-A | Antiarthritic agents | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-09-15 | — | — | US | disclosed |
| US-4956372-A | ANTIRHEUMATOID AND IMMUNOMODULATORS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0310096-A2 | Novel cyclic anthranilic acid derivatives and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |