Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 13/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994520 | 0.91 | KDM4E (0.44) | ACEACE2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7306289 | 0.89 | ACE (0.47) | ACEACE2CPT2CPT1ACHRM2 | |
| SCHEMBL7290318 | 0.88 | CPT2 (0.51) | ACEACE2CPT2CPT1ASMN1; SMN2 | |
| SCHEMBL9182343 | 0.88 | CPT2 (0.51) | ACEACE2CPT2CPT1ASMN1; SMN2 | |
| SCHEMBL9185740 | 0.85 | MEN1 (0.46) | ACEACE2CPT2CPT1ATSHR | |
| SCHEMBL9484859 | 0.85 | ACE (0.56) | ACEACE2CHRM2CHRM1CHRM3 | |
| SCHEMBL7283951 | 0.82 | F2 (0.43) | ACESMN1; SMN2ALDH1A1 | |
| SCHEMBL8306955 | 0.81 | CPT2 (0.50) | ACECPT2CPT1ALMNATSHR | |
| SCHEMBL9871268 | 0.80 | PREP (0.56) | ACEACE2ALDH1A1 | |
| SCHEMBL9257303 | 0.80 | MEN1 (0.52) | ACEACE2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401760-A | Thiazoline derivative for treating amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-28 | — | — | US | disclosed |