Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.84 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | BRD4 | O60885 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CDK9 | P50750 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600776 | 0.92 | EPHX1 (0.73) | EPHX1RAB9ANPC1POLBALDH1A1 | |
| SCHEMBL8600781 | 0.92 | EPHX1 (0.73) | EPHX1RAB9ANPC1POLBALDH1A1 | |
| SCHEMBL23431981 | 0.92 | EPHX1 (1.00) | EPHX1RAB9ANPC1POLBALDH1A1 | |
| SCHEMBL23432014 | 0.92 | EPHX1 (1.00) | EPHX1RAB9ANPC1POLBALDH1A1 | |
| SCHEMBL12196136 | 0.92 | EPHX1 (1.00) | EPHX1RAB9ANPC1POLBALDH1A1 | |
| SCHEMBL3894602 | 0.86 | EPHX1 (0.65) | EPHX1RAB9ANPC1POLBALDH1A1 | |
| SCHEMBL3894606 | 0.86 | EPHX1 (0.65) | EPHX1RAB9ANPC1POLBALDH1A1 | |
| SCHEMBL347864 | 0.85 | NPC1 (0.69) | EPHX1RAB9ANPC1POLBALDH1A1 | |
| SCHEMBL1871093 | 0.84 | NPC1 (0.73) | EPHX1RAB9ANPC1POLBALDH1A1 | |
| SCHEMBL19932335 | 0.83 | NPC1 (0.71) | EPHX1RAB9ANPC1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455300-B1 | Barbituric acid derivatives having insecticidal activity | DUPHAR INT RES (NL) | 1995-06-28 | — | — | EP | disclosed |
| US-5164396-A | Control of aphids | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-11-17 | — | — | US | disclosed |
| EP-0455300-A1 | Barbituric acid derivatives having insecticidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1991-11-06 | — | — | EP | disclosed |