Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | VCP | P55072 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600781 | 1.00 | EPHX1 (0.73) | EPHX1NPC1RAB9AALDH1A1BRD4 | |
| SCHEMBL9178993 | 0.92 | EPHX1 (0.84) | EPHX1NPC1RAB9AALDH1A1BRD4 | |
| SCHEMBL23432014 | 0.84 | EPHX1 (1.00) | EPHX1NPC1RAB9AALDH1A1BRD4 | |
| SCHEMBL23431981 | 0.84 | EPHX1 (1.00) | EPHX1NPC1RAB9AALDH1A1BRD4 | |
| SCHEMBL12196136 | 0.84 | EPHX1 (1.00) | EPHX1NPC1RAB9AALDH1A1BRD4 | |
| SCHEMBL8598568 | 0.83 | NPC1 (0.52) | EPHX1NPC1RAB9AALDH1A1BRD4 | |
| SCHEMBL6296162 | 0.83 | NAMPT (0.57) | EPHX1NPC1RAB9AALDH1A1POLB | |
| SCHEMBL3894606 | 0.79 | EPHX1 (0.65) | EPHX1NPC1RAB9AALDH1A1BRD4 | |
| SCHEMBL3894602 | 0.79 | EPHX1 (0.65) | EPHX1NPC1RAB9AALDH1A1BRD4 | |
| SCHEMBL8598520 | 0.78 | HDAC3 (0.64) | KDM4EMEN1GAAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |