Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307268 | 0.93 | TDP1 (0.60) | TDP1MAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL11801841 | 0.90 | TDP1 (0.67) | TDP1MAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL8845796 | 0.88 | TDP1 (0.69) | TDP1MAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL28422311 | 0.88 | TDP1 (0.64) | TDP1MAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL8003106 | 0.85 | HDAC1 (0.63) | TDP1MAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL94886 | 0.84 | TDP1 (0.75) | TDP1MAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL2322398 | 0.84 | KMT2A (0.70) | TDP1MAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL6602564 | 0.83 | CES1 (0.58) | TDP1MAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL3227181 | 0.81 | ERCC5 (0.53) | MAPTKMT2AMEN1KDM4EALOX15 | |
| SCHEMBL4828357 | 0.81 | CES1 (0.59) | TDP1MAPTKMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527099-A | Beta-diketone for resisting plant pathogenic fungi | 浙江清华长三角研究院 | 2021-10-22 | — | — | CN | claimed |
| CN-117357594-A | Application of heavy essential oil in preparation of inflammation relieving medicine | 中国热带农业科学院农产品加工研究所 | 2024-01-09 | — | — | CN | disclosed |
| CN-113527099-A | Beta-diketone for resisting plant pathogenic fungi | 浙江清华长三角研究院 | 2021-10-22 | — | — | CN | disclosed |
| US-9096532-B2 | Pyrazole inhibitors of COX-2 and sEH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140038923-A1 | PYRAZOLE INHIBITORS OF COX-2 AND SEH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-02-06 | — | — | US | disclosed |
| EP-0454623-B1 | Process for the production of linear 1,3-diketones | CIBA GEIGY AG (CH) | 1995-09-13 | — | — | EP | disclosed |
| WO-1994024095-A1 | IMMUNOSUPPRESSIVE AGENTS | ABBOTT LABORATORIES (US) | 1994-10-27 | — | — | WO | disclosed |
| US-5344992-A | Claisen condensation | CIBA-GEIGY CORPORATION (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0454623-A1 | Process for the production of linear 1,3-diketones | CIBA-GEIGY AG (CH) | 1991-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140038923-A1 | PYRAZOLE INHIBITORS OF COX-2 AND SEH | PTGES2, PTGS2, PTGES3 | TDP1 4455/4885MAPT 3652/4885KMT2A 2914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.