Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877680 | 0.77 | POLB (0.32) | BCL2L1MCL1MEN1KMT2APOLB | |
| SCHEMBL14138169 | 0.69 | MAPT (0.32) | — | |
| SCHEMBL9175937 | 0.68 | POLB (0.31) | BCL2L1MCL1POLBCASP6CTDSP1 | |
| SCHEMBL9172494 | 0.67 | BCL2L1 (0.32) | BCL2L1MCL1MEN1KMT2APOLB | |
| SCHEMBL21081912 | 0.64 | MEN1 (0.35) | MEN1KMT2APOLBCASP6CTDSP1 | |
| SCHEMBL8942894 | 0.61 | — | — | |
| SCHEMBL1300378 | 0.61 | — | — | |
| SCHEMBL9173280 | 0.61 | — | — | |
| SCHEMBL30430603 | 0.60 | CHRNB2 (0.35) | — | |
| SCHEMBL28948543 | 0.57 | RAB9A (0.51) | KMT2APOLBCTDSP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459160-A | Antilipemic agents | TSUMURA & CO. (JP) | 1995-10-17 | — | — | US | disclosed |
| US-5272172-A | Iridoid derivatives and the use thereof as a drug | TSUMURA & CO. (JP) | 1993-12-21 | — | — | US | disclosed |
| EP-0505572-A1 | IRIDOIDE DERIVATIVE AND ITS USE AS MEDICINE | TSUMURA & CO. (JP) | 1992-09-30 | — | — | EP | disclosed |