Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.50 |
| ▸ | CTSK | P43235 | 10/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940839 | 1.00 | CTSS (0.50) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL9181382 | 1.00 | CTSS (0.50) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL13318956 | 0.86 | CTSS (0.59) | CTSSCTSKCTSLCTSB | |
| SCHEMBL3022636 | 0.86 | CTSS (0.59) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5997785 | 0.86 | CTSS (0.59) | CTSSCTSKCTSLCTSB | |
| SCHEMBL23036809 | 0.86 | CTSS (0.49) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL23273778 | 0.86 | CTSS (0.49) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL8141271 | 0.86 | CTSS (0.49) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL13318958 | 0.86 | CTSS (0.59) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6837916 | 0.83 | CTSK (0.56) | CTSSCTSKCTSLCTSBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420347-A | Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-glycyl-D-alanine | PFIZER INC. (US) | 1995-05-30 | — | — | US | disclosed |
| US-5371187-A | Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor | PFIZER INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-5286904-A | Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-glycyl-D-alanine | PFIZER INC. (US) | 1994-02-15 | — | — | US | disclosed |
| US-5248820-A | Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor | PFIZER INC. (US) | 1993-09-28 | — | — | US | disclosed |
| US-5245079-A | Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-glycyl-D-alanine | PFIZER INC. (US) | 1993-09-14 | — | — | US | disclosed |
| US-5185464-A | Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor | PFIZER INC. (US) | 1993-02-09 | — | — | US | disclosed |
| US-5136020-A | Crystalline n-(s-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor | PFIZER INC. (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0258032-B1 | PROCESSES AND INTERMEDIATES FOR N-(S-3-ALKYLHEPTANOYL)-D-GAMMA-GLUTAMYL-GLYCYL-D-ALANINE | PFIZER INC. (US) | 1992-07-29 | — | — | EP | disclosed |
| US-5134225-A | Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-D-alanine | PFIZER INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0259084-B1 | CRYSTALLINE N-(S-3-METHYLHEPTANOYL)-D-GAMMA-GLUTAMYL-GLYCYL-D-ALANINE, AND PROCESSES AND INTERMEDIATES THEREFOR | PFIZER INC. (US) | 1992-07-22 | — | — | EP | disclosed |
| CN-1017436-B | PEPTIDE CONTAINING IMMUNOEXCITANT | PFIZER (US) | 1992-07-15 | — | — | CN | disclosed |
| EP-0227306-B1 | PEPTIDE IMMUNOSTIMULANTS | PFIZER INC. (US) | 1989-09-13 | — | — | EP | disclosed |
| US-4767743-A | ANTIINFECTION AGENTS | PFIZER INC. (US) | 1988-08-30 | — | — | US | disclosed |
| WO-1988001613-A1 | CRYSTALLINE N-(S-3-METHYLHEPTANOYL)-D-GAMMA-GLUTAMYL-GLYCYL-D-ALANINE, AND PROCESSES AND INTERMEDIATES THEREFOR | PFIZER INC. (US) | 1988-03-10 | — | — | WO | disclosed |
| WO-1988001612-A1 | PROCESSES AND INTERMEDIATES FOR N-(S-3-ALKYL-HEPTANOYL)-D-GAMMA-GLUTAMYL-GLYCYL-D-ALANINE | PFIZER INC. (US) | 1988-03-10 | — | — | WO | disclosed |
| EP-0259084-A2 | Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor | PFIZER INC. (US) | 1988-03-09 | — | — | EP | disclosed |
| EP-0258032-A2 | Processes and intermediates for N-(S-3-alkylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine | PFIZER INC. (US) | 1988-03-02 | — | — | EP | disclosed |
| EP-0227306-A2 | Peptide immunostimulants | PFIZER INC. (US) | 1987-07-01 | — | — | EP | disclosed |
| CN-86107931-A | PEPTIDE CONTAINING IMMUNOEXCITANT | — | 1987-07-01 | — | — | CN | disclosed |