SCHEMBL9181591

SCHEMBL9181591

CC(=O)NC1(CO)CCNC1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
KMT2A Q03164 1/20 0.35
BAZ2A Q9UIF9 1/20 0.31
PIK3R1 P27986 2/20 0.30
PIK3CA P42336 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22499953 0.83 KDM4E (0.32) KDM4EKMT2APIK3R1PIK3CA
SCHEMBL9183418 0.80 BAZ2A (0.33) BAZ2A
SCHEMBL13941597 0.78
SCHEMBL4726064 0.77 P2RX7 (0.34) KDM4EKMT2A
SCHEMBL13738955 0.77 P2RX7 (0.34) KDM4EKMT2A
SCHEMBL21526626 0.77 KDM4E (0.37) KDM4EKMT2ABAZ2A
SCHEMBL9083522 0.76
Acetic Acid SCHEMBL23244955 0.74 KDM4E (0.35) KDM4EKMT2A
SCHEMBL976812 0.74 MME (0.44)
SCHEMBL23715196 0.74 MME (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326916-A2 Quinolone- and naphthyridone-carboxylic acid derivatives, method for their preparation and antibacterial agents and food additives containing them BAYER AG (DE) 1989-08-09 EP claimed
US-5453422-A Animal growth promoters BAYER AKTIENGESELLSCHAFT (DE) 1995-09-26 US disclosed
US-5284842-A Active against gramnegative bacteria BAYER AKTIENGESELLSCHAFT (DE) 1994-02-08 US disclosed
US-5252734-A Antibacterial 5-alkylquinolonecarboxylic acids BAYER AKTIENGESELLSCHAFT (DE) 1993-10-12 US disclosed
US-5173484-A Animal growth regulators BAYER AKTIENGESELLSCHAFT (DE) 1992-12-22 US disclosed
US-5140033-A For prevention or treatment of bacterial infections in humans or animals BAYER AKTIENGESELLSCHAFT (DE) 1992-08-18 US disclosed
EP-0391132-A1 5-Alkylquinolinone carboxylic acids BAYER AG (DE) 1990-10-10 EP disclosed
EP-0326916-A2 Quinolone- and naphthyridone-carboxylic acid derivatives, method for their preparation and antibacterial agents and food additives containing them BAYER AG (DE) 1989-08-09 EP disclosed