Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17717923 | 0.82 | MEN1 (0.56) | HPGDMEN1KMT2AMAPTGAA | |
| SCHEMBL5443739 | 0.79 | HPGD (0.46) | HPGDMEN1KMT2AMAPTGAA | |
| SCHEMBL17717965 | 0.78 | MAPT (0.62) | HPGDMEN1KMT2AMAPTGAA | |
| SCHEMBL2680328 | 0.78 | MEN1 (0.62) | HPGDMEN1KMT2AMAPTGAA | |
| SCHEMBL11550773 | 0.77 | OPRK1 (0.62) | HPGDMEN1KMT2AMAPTHTT | |
| SCHEMBL437784 | 0.77 | HPGD (0.59) | HPGDMEN1KMT2AMAPTGAA | |
| SCHEMBL4995780 | 0.76 | OPRL1 (0.41) | MEN1KMT2AMAPTGAAL3MBTL1 | |
| SCHEMBL8025052 | 0.76 | OPRL1 (0.41) | MEN1KMT2AMAPTGAAL3MBTL1 | |
| SCHEMBL11652238 | 0.76 | MEN1 (0.50) | HPGDMEN1KMT2AMAPTGAA | |
| SCHEMBL9496590 | 0.76 | MEN1 (0.50) | HPGDMEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455300-B1 | Barbituric acid derivatives having insecticidal activity | DUPHAR INT RES (NL) | 1995-06-28 | — | — | EP | disclosed |
| US-5164396-A | Control of aphids | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-11-17 | — | — | US | disclosed |
| EP-0455300-A1 | Barbituric acid derivatives having insecticidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1991-11-06 | — | — | EP | disclosed |