SCHEMBL2680328

SCHEMBL2680328

O=C1CC(=O)N(c2ccccc2)C(=O)N1Cc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
MAPT P10636 4/20 0.62
POLB P06746 3/20 0.62
USP2 O75604 2/20 0.62
KDM4E B2RXH2 1/20 0.62
RECQL P46063 1/20 0.62
BLM P54132 1/20 0.62
F2 P00734 1/20 0.53
PLG P00747 1/20 0.53
ELANE P08246 1/20 0.53
CTSG P08311 1/20 0.53
CMA1 P23946 1/20 0.53
CTRC Q99895 1/20 0.53
GAA P10253 1/20 0.51
HTT P42858 1/20 0.51
HSD17B10 Q99714 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
HPGD P15428 2/20 0.50
ENPP2 Q13822 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17717903 0.92 MEN1 (0.54) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL5448612 0.86 KMT2A (0.80) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL17717923 0.84 MEN1 (0.56) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL11651629 0.84 KMT2A (0.76) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL11652238 0.82 MEN1 (0.50) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL5443739 0.81 HPGD (0.46) MEN1KMT2AMAPTUSP2ELANE
SCHEMBL17717965 0.80 MAPT (0.62) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL437784 0.80 HPGD (0.59) MEN1KMT2AMAPTGAAHPGD
SCHEMBL19998149 0.79 KMT2A (0.71) MEN1KMT2AMAPTPOLBUSP2
SCHEMBL9496590 0.79 MEN1 (0.50) MEN1KMT2AMAPTPOLBUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0951896-B1 Radically polymerizable dental material IVOCLAR VIVADENT AG (LI) 2005-12-21 EP claimed
US-6281271-B1 BLEND OF POLYMER AND FILLER IVOCLAR AG (LI) 2001-08-28 US claimed
US-12605307-B2 Dental composite material KULZER GMBH (DE) 2026-04-21 US disclosed
US-12365811-B2 Polymerizable composition KULZER GMBH (DE) 2025-07-22 US disclosed
US-20250092176-A1 THIOL URETHANE GROUP-CONTAINING POLYMERIZABLE COMPOSITION KULZER GMBH (DE) 2025-03-20 US disclosed
US-20240352274-A2 POLYMERIZABLE COMPOSITION KULZER GMBH (DE) 2024-10-24 US disclosed
US-20240182744-A1 POLYMERIZABLE COMPOSITION KULZER & CO GMBH (DE) 2024-06-06 US disclosed
US-20240164995-A1 DENTAL COMPOSITE MATERIAL KULZER GMBH (DE) 2024-05-23 US disclosed
EP-4346744-A1 THIOL URETHANE GROUP-CONTAINING POLYMERIZABLE COMPOSITION Kulzer GmbH (DE) 2024-04-10 EP disclosed
EP-4048226-A1 DENTAL COMPOSITE MATERIAL Kulzer GmbH (DE) 2022-08-31 EP disclosed
EP-4048708-A1 POLYMERIZABLE COMPOSITION Kulzer GmbH (DE) 2022-08-31 EP disclosed
US-8697772-B2 Polymerizable phosphoric acid derivatives comprising a polyalicylic structure element VOCO GMBH (DE) 2014-04-15 US disclosed
WO-2013126377-A1 STRUCTURAL ACRYLIC ADHESIVE 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-08-29 WO disclosed
US-20130120839-A1 CELLULOSE ACYLATE FILM, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-05-16 US disclosed
US-20120259032-A1 MULTICOMPONENT SYSTEM FOR PRODUCING A DENTAL MATERIAL MUHLBAUER TECHNOLOGY GMBH (DE) 2012-10-11 US disclosed
US-20120115108-A1 POLYMERIZABLE PHOSPHORIC ACID DERIVATIVES COMPRISING A POLYALICYLIC STRUCTURE ELEMENT VOCO GMBH (DE) 2012-05-10 US disclosed
US-7278849-B2 Dental prosthesis with metal-free anchoring elements IVOCLAR VIVADENT AG (LI) 2007-10-09 US disclosed
US-20040038182-A1 Dental prosthesis with metal-free anchoring elements IVOCLAR VIVADENT AG (LI) 2004-02-26 US disclosed
US-6281271-B1 BLEND OF POLYMER AND FILLER IVOCLAR AG (LI) 2001-08-28 US disclosed
US-4097475-A FOR POLYESTERS AND BLENDS WITH CELLULOSE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250092176-A1 THIOL URETHANE GROUP-CONTAINING POLYMERIZABLE COMPOSITION TST, MTHFD2, TMT1A MEN1 3090/4885KMT2A 3156/4885MAPT 212/4885
US-20240164995-A1 DENTAL COMPOSITE MATERIAL CAD, PUF60, ALG3 MEN1 1990/4885KMT2A 1785/4885MAPT 46/4885
US-12605307-B2 Dental composite material ARCN1, CAD, ITGA1 MEN1 2053/4885KMT2A 2530/4885MAPT 113/4885
US-20120115108-A1 POLYMERIZABLE PHOSPHORIC ACID DERIVATIVES COMPRISING A POLYALICYLIC STRUCTURE ELEMENT CAD, PCBP1, PPIP5K2 MEN1 3006/4885KMT2A 2122/4885MAPT 258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.