Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9182882 | 0.84 | PARP10 (0.47) | ALDH1A1MEN1KMT2ATSHRNR1H4 | |
| SCHEMBL9184984 | 0.81 | TSHR (0.50) | ALDH1A1KMT2AANPEPTP53TSHR | |
| Terephthalic Acid SCHEMBL28416525 | 0.81 | MEN1 (0.47) | ALDH1A1MEN1CYP1A2KMT2ATP53 | |
| SCHEMBL18388718 | 0.79 | TSHR (0.48) | ALDH1A1KMT2AANPEPTP53TSHR | |
| SCHEMBL11407130 | 0.79 | AOC3 (0.50) | — | |
| SCHEMBL12646113 | 0.78 | RXRA (0.43) | ALDH1A1MEN1CYP1A2KMT2AANPEP | |
| SCHEMBL13660065 | 0.77 | RXRA (0.42) | ALDH1A1MEN1CYP1A2KMT2AANPEP | |
| SCHEMBL8432358 | 0.75 | NR1H4 (0.50) | ALDH1A1MEN1CYP1A2KMT2AANPEP | |
| SCHEMBL22051404 | 0.75 | TSHR (0.52) | ALDH1A1KMT2AANPEPTP53TSHR | |
| SCHEMBL19164555 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378728-A | Benzoic acid derivatives as antidiabetic agents | SANDOZ LTD. (CH) | 1995-01-03 | — | — | US | claimed |
| US-5378728-A | Benzoic acid derivatives as antidiabetic agents | SANDOZ LTD. (CH) | 1995-01-03 | — | — | US | disclosed |