Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.54 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.54 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.54 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181258 | 0.98 | GABRA1 (0.53) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL9176703 | 0.98 | GABRA1 (0.53) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL9177990 | 0.98 | GABRA1 (0.53) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL9182118 | 0.98 | GABRA1 (0.53) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL9176771 | 0.98 | GABRA1 (0.53) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL9183829 | 0.98 | GABRA1 (0.53) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL9181950 | 0.98 | GABRA1 (0.53) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL9177934 | 0.98 | GABRA1 (0.53) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL11799626 | 0.93 | PTGS2 (0.50) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL11795599 | 0.91 | GABRA1 (0.50) | GABRA1GABRB1GABRB2GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5473003-A | A styrene copolymer blend comprising a stabilizer for heat, oxidation, chemical and actinic radiation resistance | CIBA-GEIGY CORPORATION (US) | 1995-12-05 | — | — | US | disclosed |