SCHEMBL9181998

SCHEMBL9181998

CCCCCCCCCCC1=CC(=O)C=CC1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 1.00
BACE1 P56817 1/20 1.00
ALOX5 P09917 15/20 0.53
PTGS2 P35354 5/20 0.53
GLS2 Q9UI32 1/20 0.53
PTPN1 P18031 1/20 0.49
STAT3 P40763 1/20 0.47
MPEG1 Q2M385 7/20 0.42
XIAP P98170 2/20 0.42
GPR84 Q9NQS5 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
PTGES O14684 1/20 0.42
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31203727 1.00 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL28564810 1.00 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL10701374 1.00 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL3264783 1.00 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL10704172 1.00 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL28549544 1.00 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL11018415 1.00 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL10702354 1.00 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL8782213 1.00 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2
SCHEMBL20875697 1.00 ACHE (1.00) ACHEBACE1ALOX5PTGS2GLS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0327318-B1 Heat-sensitive recording materials FUJI PHOTO FILM CO LTD (JP) 1995-07-19 EP disclosed
EP-0327318-A2 Heat-sensitive recording materials FUJI PHOTO FILM CO., LTD. (JP) 1989-08-09 EP disclosed
EP-0323887-A2 Heat-sensitive diazo recording materials FUJI PHOTO FILM CO., LTD. (JP) 1989-07-12 EP disclosed
EP-0288240-A2 Heat-sensitive diazo recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-10-26 EP disclosed