Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 1.00 |
| ▸ | BACE1 | P56817 | 1/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 15/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.53 |
| ▸ | GLS2 | Q9UI32 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.42 |
| ▸ | XIAP | P98170 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31203727 | 1.00 | ACHE (1.00) | ACHEBACE1ALOX5PTGS2GLS2 | |
| SCHEMBL28564810 | 1.00 | ACHE (1.00) | ACHEBACE1ALOX5PTGS2GLS2 | |
| SCHEMBL10701374 | 1.00 | ACHE (1.00) | ACHEBACE1ALOX5PTGS2GLS2 | |
| SCHEMBL10704172 | 1.00 | ACHE (1.00) | ACHEBACE1ALOX5PTGS2GLS2 | |
| SCHEMBL28549544 | 1.00 | ACHE (1.00) | ACHEBACE1ALOX5PTGS2GLS2 | |
| SCHEMBL11018415 | 1.00 | ACHE (1.00) | ACHEBACE1ALOX5PTGS2GLS2 | |
| SCHEMBL10702354 | 1.00 | ACHE (1.00) | ACHEBACE1ALOX5PTGS2GLS2 | |
| SCHEMBL8782213 | 1.00 | ACHE (1.00) | ACHEBACE1ALOX5PTGS2GLS2 | |
| SCHEMBL20875697 | 1.00 | ACHE (1.00) | ACHEBACE1ALOX5PTGS2GLS2 | |
| SCHEMBL9181998 | 1.00 | ACHE (1.00) | ACHEBACE1ALOX5PTGS2GLS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030607-A1 | TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS | EDISON PHARMACEUTICALS, INC. (US) | 2010-03-18 | — | — | WO | claimed |
| CN-1938040-A | Oxytocin controlled release formulations and methods of using same | PR PHARMACEUTICALS (US) | 2007-03-28 | — | — | CN | claimed |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | claimed |
| WO-2024054871-A1 | METHODS OF PRODUCING 2,3,5,6-ALKYL-1,4-BENZOQUINONES | PTC THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| CN-110902804-A | Method for removing pollutants in wastewater by utilizing thermally-assisted benzoquinone wastewater to catalyze persulfate | 长江师范学院 | 2020-03-24 | — | — | CN | disclosed |
| WO-2013058582-A3 | PREPARATION METHOD FOR ANSAMYCIN GLYCOSIDE USING GLYCOSYLTRANSFERASE | 한국생명공학연구원 (KR) | 2013-07-04 | — | — | WO | disclosed |
| WO-2013058582-A2 | PREPARATION METHOD FOR ANSAMYCIN GLYCOSIDE USING GLYCOSYLTRANSFERASE | 한국생명공학연구원 (KR) | 2013-04-25 | — | — | WO | disclosed |
| US-8309639-B2 | Rubber compositions comprising benzoquinones and the use thereof in golf balls | ACUSHNET COMPANY (US) | 2012-11-13 | — | — | US | disclosed |
| US-7855192-B2 | Macrolactams by engineered biosynthesis | KOSAN BIOSCIENCES, INC. (US) | 2010-12-21 | — | — | US | disclosed |
| US-20100022329-A1 | RUBBER COMPOSITIONS COMPRISING BENZOQUINONES AND THE USE THEREOF IN GOLF BALLS | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2010-01-28 | — | — | US | disclosed |
| EP-2121957-A1 | MACROLACTAMS BY ENGINEERED BIOSYNTHESIS | Kosan Biosciences, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008094438-A1 | MACROLACTAMS BY ENGINEERED BIOSYNTHESIS | KOSAN BIOSCIENCES INCORPORATED (US) | 2008-08-07 | — | — | WO | disclosed |
| US-20080188450-A1 | A 2-azabicyclo(16.3.1)docosa-1(21),4,6,10,18-penntaen-9-ylcarbamate derivative; Heat shock protein 90 inhibitors; hyperproliferative disease, breast cancer, ovarian cancer, leukemia, colon cancer, lung cancer | KOSAN BIOSCIENCES INCORPORATED | 2008-08-07 | — | — | US | disclosed |
| US-20070213442-A1 | Rubber compositions comprising benzoquinones and the use thereof in golf balls | ACUSHNET COMPANY | 2007-09-13 | — | — | US | disclosed |
| US-7241754-B2 | 2-Desmethyl ansamycin compounds | KOSAN BIOSCIENCES, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20050026894-A1 | 2-Desmethyl ansamycin compounds | KOSAN BIOSCIENCES, INC. | 2005-02-03 | — | — | US | disclosed |
| WO-2005009345-A2 | 2-DESMETHYL ANSAMYCIN COMPOUNDS | KOSAN BIOSCIENCES, INC. (US) | 2005-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026894-A1 | 2-Desmethyl ansamycin compounds | RPSA, RPS6KB2, RPS2 | ACHE 3963/4885BACE1 3985/4885ALOX5 4695/4885 |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | KRT18, GPX4, NOX4 | ACHE 1556/4885BACE1 4112/4885ALOX5 1018/4885 |
| US-20080188450-A1 | A 2-azabicyclo(16.3.1)docosa-1(21),4,6,10,18-penntaen-9-ylcarbamate derivative; Heat shock protein 90 inhibitors; hyperproliferative disease, breast cancer, ovarian cancer, leukemia, colon cancer, lung cancer | HSP90AB2P, HSP90AB1, HSPA1B | ACHE 4875/4885BACE1 4837/4885ALOX5 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.