SCHEMBL9182016

SCHEMBL9182016

Cc1cc(Cc2ccccc2C)c(O)c(/N=N/c2ccc(Cl)cc2[N+](=O)[O-])c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.42
KMT2A Q03164 9/20 0.42
MAPT P10636 8/20 0.42
ALDH1A1 P00352 4/20 0.42
HTT P42858 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
POLB P06746 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
KDM4E B2RXH2 2/20 0.42
RECQL P46063 2/20 0.42
HSP90AA1 P07900 1/20 0.42
THRB P10828 1/20 0.42
BLM P54132 1/20 0.42
BCL2L1 Q07817 1/20 0.42
MCL1 Q07820 1/20 0.42
HKDC1 Q2TB90 1/20 0.42
MAPK1 P28482 3/20 0.41
UBE2I P63279 1/20 0.41
SAE1 Q9UBE0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9179210 0.88 PTPN11 (0.43) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL11874364 0.83 NPC1 (0.44) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL27594032 0.81 MEN1 (0.39) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL11873776 0.80 GPR35 (0.44) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL11873767 0.80 GPR35 (0.44) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL1509538 0.77 ALDH1A1 (0.46) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL29603532 0.76 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL7759727 0.76 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL7759721 0.76 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL9182022 0.75 MAPT (0.42) MEN1KMT2AMAPTALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0380840-B1 Method of preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA LTD (JP) 1995-05-17 EP disclosed
US-5187289-A Method of preparing 2-phenyl benzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1993-02-16 US disclosed
EP-0263905-B1 METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES CHEMIPRO KASEI KAISHA, LTD. (JP) 1992-04-15 EP disclosed
US-5104992-A METHOD OF PREPARING 2-PHENYL BENEZOTHRIAZOLES CHEMIPRO KASEI KAISHA, LTD. (JP) 1992-04-14 US disclosed
EP-0257151-B1 METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES CHEMIPRO KASEI KAISHA, LTD. (JP) 1992-01-29 EP disclosed
EP-0380840-A1 Method of preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1990-08-08 EP disclosed
EP-0380839-A1 Method of preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1990-08-08 EP disclosed
US-4943637-A Method for preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1990-07-24 US disclosed
EP-0263905-A1 Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides CHEMIPRO KASEI KAISHA, LTD. (JP) 1988-04-20 EP disclosed
EP-0160246-A1 A method for producing A 2-phenylbenzotriazole SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-11-06 EP disclosed