Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL721623 | 0.88 | THRB (0.53) | THRBTSHRALDH1A1EGLN1MAPT | |
| Succinic Acid SCHEMBL3871268 | 0.88 | THRB (0.53) | THRBTSHRALDH1A1EGLN1MAPT | |
| Glutarate SCHEMBL3866346 | 0.85 | THRB (0.50) | THRBTSHRALDH1A1EGLN1HSD17B10 | |
| Adipic Acid SCHEMBL3877653 | 0.85 | THRB (0.50) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL7090019 | 0.83 | THRB (0.58) | THRBTSHRALDH1A1EGLN1MAPT | |
| Bicarbonate SCHEMBL10996730 | 0.82 | THRB (0.59) | THRBTSHRALDH1A1EGLN1MAPT | |
| SCHEMBL27834847 | 0.82 | THRB (0.59) | THRBTSHRALDH1A1EGLN1MAPT | |
| Acetic Acid SCHEMBL28298395 | 0.82 | THRB (0.59) | THRBTSHRALDH1A1EGLN1MAPT | |
| SCHEMBL19409375 | 0.82 | THRB (0.64) | THRBTSHRALDH1A1EGLN1MAPT | |
| SCHEMBL15030 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432727-B1 | Electrophotographic light-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 1995-07-05 | — | — | EP | disclosed |
| US-5227272-A | Layer containing inorganic photoconductor and binder resin with block copolymer composed of acidic component and hydrocarbyl methacrylate component | FUJI PHOTO FILM CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0432727-A2 | Electrophotographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-06-19 | — | — | EP | disclosed |