Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9182772 | 1.00 | L3MBTL1 (0.44) | L3MBTL1LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL9411054 | 1.00 | L3MBTL1 (0.44) | L3MBTL1LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL11407417 | 0.81 | NPC1 (0.47) | L3MBTL1LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL5958327 | 0.80 | LMNA (0.48) | L3MBTL1LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL5958328 | 0.80 | LMNA (0.48) | L3MBTL1LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL6348030 | 0.75 | LMNA (0.45) | L3MBTL1LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL5197529 | 0.75 | SMN1; SMN2 (0.50) | L3MBTL1LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL5197523 | 0.75 | SMN1; SMN2 (0.50) | L3MBTL1LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL6348031 | 0.75 | LMNA (0.45) | L3MBTL1LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL3389005 | 0.74 | LMNA (0.39) | L3MBTL1LMNAMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420298-A | Antiinflammatory agents by inhibition of leukotrienes | ZENECA LIMITED (GB) | 1995-05-30 | — | — | US | claimed |
| EP-0586229-A1 | 3-Hydroxy-3-(subst-akyl)-pyrrolidines as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1994-03-09 | — | — | EP | claimed |
| US-5420298-A | Antiinflammatory agents by inhibition of leukotrienes | ZENECA LIMITED (GB) | 1995-05-30 | — | — | US | disclosed |
| EP-0586229-A1 | 3-Hydroxy-3-(subst-akyl)-pyrrolidines as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1994-03-09 | — | — | EP | disclosed |