SCHEMBL7108955

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28256664	0.95	APP (0.46)	APPCYP2C19PTGS1PDE4ALMNA
	SCHEMBL918312	0.94	APP (0.50)	APPCYP2C19PTGS1PDE4ALMNA
	SCHEMBL2121438	0.92	APP (0.48)	APPCYP2C19PTGS1PDE4ALMNA
	SCHEMBL818333	0.90	APP (0.61)	APPCYP2C19LMNASLC6A6BLM
	SCHEMBL3181168	0.90	APP (0.42)	APPCYP2C19PTGS1PDE4ALMNA
	SCHEMBL12541657	0.89	APP (0.46)	APPCYP2C19PTGS1PDE4ALMNA
	SCHEMBL11517230	0.88	APP (0.65)	APPCYP2C19LMNASLC6A6BLM
	SCHEMBL15305904	0.88	PAOX (0.52)	APPCYP2C19EPHX2RELACA2
	SCHEMBL21518352	0.88	ALDH1A1 (0.59)	EPHX2RELACA2TSHRALDH1A1
	SCHEMBL21518429	0.88	TSHR (0.52)	APPEPHX2RELACA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.