Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10789114 | 0.84 | TSHR (0.39) | EPHX1TSHRALDH1A1LMNAADH1B | |
| SCHEMBL11688228 | 0.79 | TSHR (0.44) | EPHX1TSHRTHRBALDH1A1PPARA | |
| SCHEMBL9651268 | 0.76 | TSHR (0.41) | EPHX1TSHRTHRBALDH1A1LMNA | |
| SCHEMBL235198 | 0.70 | TSHR (0.41) | EPHX1TSHRTHRBALDH1A1PPARA | |
| SCHEMBL234442 | 0.70 | TSHR (0.35) | EPHX1TSHRTHRBALDH1A1LMNA | |
| SCHEMBL9816794 | 0.70 | EPHX1 (0.52) | EPHX1TSHRTHRBALDH1A1PPARA | |
| SCHEMBL234957 | 0.70 | TSHR (0.41) | EPHX1TSHRTHRBALDH1A1PPARA | |
| SCHEMBL234029 | 0.70 | EPHX1 (0.52) | EPHX1TSHRTHRBALDH1A1PPARA | |
| SCHEMBL233914 | 0.69 | TSHR (0.45) | EPHX1TSHRTHRBALDH1A1LMNA | |
| SCHEMBL234298 | 0.69 | ADH1B (0.30) | ADH1BADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316696-B1 | Organopolysiloxane elastomers having improved electrical properties and insulators coated therewith | WACKER CHEMIE GMBH (DE) | 1995-07-19 | — | — | EP | disclosed |
| EP-0316696-A2 | Organopolysiloxane elastomers having improved electrical properties and insulators coated therewith | WACKER-CHEMIE GMBH (DE) | 1989-05-24 | — | — | EP | disclosed |
| US-4822830-A | CROSSLINKED WITH AMINOORGANOSILICON COMPOUND AND ALUMINA TRIHYDRATE; MOISTURE CURED | WACKER SILICONES CORPORATION (US) | 1989-04-18 | — | — | US | disclosed |
| US-4671933-A | Method for inhibiting corrosion of metal surfaces | STAUFFER-WACKER SILICONES CORPORATION (US) | 1987-06-09 | — | — | US | disclosed |