Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654249 | 0.87 | CTSK (0.44) | CTSKPRKCAPRKCDCHRM1AKR1A1 | |
| SCHEMBL12185933 | 0.83 | FAAH (0.38) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL10666652 | 0.83 | FAAH (0.38) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL4059092 | 0.83 | CTSK (0.33) | CTSK | |
| SCHEMBL12986881 | 0.81 | CTSK (0.39) | CTSKPRKCAPRKCDCHRM1AKR1A1 | |
| SCHEMBL9184592 | 0.79 | CTSK (0.41) | CTSKPRKCAPRKCDCHRM1AKR1A1 | |
| SCHEMBL6894951 | 0.79 | CTSK (0.38) | CTSKPRKCAPRKCDCHRM1AKR1A1 | |
| SCHEMBL609519 | 0.79 | TSHR (0.38) | TSHRLMNA | |
| SCHEMBL11806348 | 0.78 | CTSK (0.36) | CTSKPRKCAPRKCDCHRM1AKR1A1 | |
| SCHEMBL13039899 | 0.78 | MAPT (0.33) | CHRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665847-A1 | CEPHEM COMPOUNDS, AND THEIR PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994010177-A1 | CEPHEM COMPOUNDS, AND THEIR PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | WO | disclosed |