Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184427 | 0.88 | KDM4E (0.53) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9184560 | 0.83 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9182449 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9186857 | 0.82 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL7750980 | 0.82 | KDM4E (0.79) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Famciclovir SCHEMBL29357294 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Famciclovir SCHEMBL2949 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Famciclovir SCHEMBL8190642 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9184386 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Famciclovir SCHEMBL7103048 | 0.79 | KDM4E (0.98) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242482-B1 | Antiviral purine derivatives and process for their preparation | BEECHAM GROUP PLC (GB) | 1995-09-06 | — | — | EP | claimed |
| US-4965270-A | Viricides | BEECHAM GROUP P.L.C. (GB) | 1990-10-23 | — | — | US | claimed |
| EP-0313289-A2 | Process for the preparation of purine compounds and intermediates therefor | BEECHAM GROUP PLC (GB) | 1989-04-26 | — | — | EP | claimed |
| EP-0298601-A1 | 6-Deoxy guanine derivatives and pyrimidine intermediates | BEECHAM GROUP PLC (GB) | 1989-01-11 | — | — | EP | claimed |
| EP-0242482-A2 | Antiviral purine derivatives and process for their preparation | BEECHAM GROUP PLC (GB) | 1987-10-28 | — | — | EP | claimed |
| EP-0242482-B1 | Antiviral purine derivatives and process for their preparation | BEECHAM GROUP PLC (GB) | 1995-09-06 | — | — | EP | disclosed |
| US-4965270-A | Viricides | BEECHAM GROUP P.L.C. (GB) | 1990-10-23 | — | — | US | disclosed |
| EP-0242482-A2 | Antiviral purine derivatives and process for their preparation | BEECHAM GROUP PLC (GB) | 1987-10-28 | — | — | EP | disclosed |