Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23086156 | 0.88 | MEN1 (0.60) | LMNAKMT2AMAPTCA1CA2 | |
| SCHEMBL8537873 | 0.79 | LMNA (0.60) | LMNAKMT2AMAPTGFERTDP1 | |
| SCHEMBL10362010 | 0.79 | LMNA (0.66) | LMNAKMT2AMAPTGFERCA1 | |
| SCHEMBL10361963 | 0.79 | LMNA (0.70) | LMNAKMT2AMAPTGFERTDP1 | |
| SCHEMBL9187308 | 0.79 | LMNA (0.56) | LMNAKMT2AMAPTGFERTDP1 | |
| SCHEMBL9185852 | 0.77 | DRD3 (0.57) | TDP1 | |
| SCHEMBL10810867 | 0.76 | LMNA (0.59) | LMNAKMT2AMAPTGFERTDP1 | |
| SCHEMBL9183543 | 0.76 | LMNA (0.59) | LMNAKMT2AMAPTGFERTDP1 | |
| SCHEMBL10361975 | 0.76 | LMNA (0.65) | LMNAKMT2AMAPTGFERCA1 | |
| SCHEMBL10361959 | 0.76 | LMNA (0.62) | LMNAKMT2AMAPTGFERCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432179-A | Antiallergens | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0598123-A1 | PIPERAZINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-25 | — | — | EP | disclosed |