Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537793 | 0.81 | P2RX7 (0.53) | — | |
| SCHEMBL9183552 | 0.79 | LMNA (0.66) | LMNAMAPTKDM4EL3MBTL1NPSR1 | |
| SCHEMBL10362010 | 0.77 | LMNA (0.66) | LMNAMAPTL3MBTL1HTTPOLB | |
| SCHEMBL10362076 | 0.76 | LMNA (0.62) | LMNAMAPTKDM4EL3MBTL1HTT | |
| SCHEMBL8540076 | 0.76 | DRD3 (0.53) | LMNAGAATDP1KMT2AMEN1 | |
| SCHEMBL10361963 | 0.74 | LMNA (0.70) | LMNAMAPTKDM4EL3MBTL1HTT | |
| SCHEMBL10361959 | 0.74 | LMNA (0.62) | LMNAMAPTL3MBTL1HTTPOLB | |
| SCHEMBL10361975 | 0.74 | LMNA (0.65) | LMNAMAPTL3MBTL1POLBGFER | |
| SCHEMBL10362411 | 0.74 | LMNA (0.58) | LMNAMAPTGAAL3MBTL1HTT | |
| SCHEMBL10361518 | 0.73 | LMNA (0.61) | LMNAMAPTHTTPOLBGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508334-B1 | Novel aminophenol derivatives and pharmaceutical compositions thereof | GREEN CROSS CORP (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5308840-A | Antioxidants, antiallergens and antiinflammatory agents | GREEN CROSS CORPORATION (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0508334-A2 | Novel aminophenol derivatives and pharmaceutical compositions thereof | THE GREEN CROSS CORPORATION (JP) | 1992-10-14 | — | — | EP | disclosed |