SCHEMBL9183752

SCHEMBL9183752

C=C(C)C(=O)OC(CC)[Si](C)(C)O[Si](C)(OC)OC

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
TSHR P16473 3/20 0.33
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7179413 0.92 TSHR (0.37) ALDH1A1TSHRTHRB
SCHEMBL3808301 0.87 ALDH1A1 (0.39) ALDH1A1TSHRTHRB
SCHEMBL4738203 0.85 TSHR (0.35) ALDH1A1TSHRTHRB
SCHEMBL1273966 0.85 TSHR (0.35) ALDH1A1TSHRTHRB
SCHEMBL7634516 0.84 TSHR (0.33) ALDH1A1TSHRTHRB
SCHEMBL21670470 0.83 ALDH1A1 (0.35) ALDH1A1TSHRTHRB
SCHEMBL195788 0.80 ALDH1A1 (0.39) ALDH1A1TSHRTHRB
SCHEMBL3477370 0.80 TSHR (0.32) TSHRTHRB
SCHEMBL1551132 0.79 THRB (0.37) ALDH1A1TSHRTHRB
SCHEMBL6575777 0.78 ALDH1A1 (0.40) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0433727-B1 Silica-core silicone-shell particles, emulsion containing the same dispersed therein, and process for producing the emulsion TOSHIBA SILICONE (JP) 1995-08-02 EP disclosed
EP-0433906-B1 Thermoplastic resin and process for producing the same TOSHIBA SILICONE (JP) 1995-07-26 EP disclosed
US-5218014-A Graft polymer formed by graft polymerization of vinyl monomer onto colloidal silica core silicone shell particles TOSHIBA SILICONE CO., LTD. (JP) 1993-06-08 US disclosed
US-5188899-A SILICA-CORE SILICONE-SHELL PARTICLES, EMULSION CONTAINING THE SAME DISPERSED THEREIN, AND PROCESS FOR PRODUCING THE EMULSION TOSHIBA SILICONE CO., LTD. (JP) 1993-02-23 US disclosed
EP-0433906-A2 Thermoplastic resin and process for producing the same TOSHIBA SILICONE CO., LTD. (JP) 1991-06-26 EP disclosed
EP-0433727-A1 Silica-core silicone-shell particles, emulsion containing the same dispersed therein, and process for producing the emulsion TOSHIBA SILICONE CO., LTD. (JP) 1991-06-26 EP disclosed