Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | PTAFR | P25105 | 2/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91928 | 0.84 | PTAFR (0.33) | FASNPTAFR | |
| SCHEMBL91881 | 0.84 | PTAFR (0.33) | FASNPTAFR | |
| SCHEMBL92005 | 0.84 | PTAFR (0.33) | FASNPTAFR | |
| SCHEMBL92009 | 0.81 | PTAFR (0.32) | FASNPTAFR | |
| SCHEMBL91926 | 0.79 | FASN (0.30) | FASN | |
| SCHEMBL12759318 | 0.77 | FASN (0.35) | FASN | |
| SCHEMBL91842 | 0.76 | HTR1A (0.35) | FASNSSTR5 | |
| SCHEMBL83414 | 0.75 | — | — | |
| SCHEMBL84086 | 0.75 | — | — | |
| SCHEMBL8939733 | 0.74 | FPR2 (0.35) | FASNFPR2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-7531106-B2 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2009-05-12 | — | — | US | disclosed |