Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 2/20 | 0.46 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9180729 | 0.89 | HTR7 (0.55) | HTR7KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL9185929 | 0.88 | HTR7 (0.57) | HTR7KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL9182728 | 0.88 | HTR7 (0.53) | HTR7KDM4EALDH1A1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL9185067 | 0.87 | HTR7 (0.52) | HTR7KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL9181655 | 0.84 | KMT2A (0.58) | HTR7KDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL219876 | 0.83 | HRH1 (0.59) | HTR7KDM4EALDH1A1HRH3BCL2 | |
| SCHEMBL9180090 | 0.82 | HRH3 (0.53) | HTR7KDM4EALDH1A1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL5686168 | 0.82 | HRH1 (0.60) | HTR7KDM4EALDH1A1HRH3BCL2 | |
| Hydrochloric Acid SCHEMBL219199 | 0.82 | HRH1 (0.60) | HTR7KDM4EALDH1A1HRH3BCL2 | |
| SCHEMBL9178327 | 0.81 | KCNA5 (0.58) | HTR7KDM4EALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432179-A | Antiallergens | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0598123-A1 | PIPERAZINE DERIVATIVE AND DRUG CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-25 | — | — | EP | disclosed |