SCHEMBL9185014

SCHEMBL9185014

ClC(Cl)(Cl)Oc1ccnnn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9183763 0.83
SCHEMBL8568961 0.75
SCHEMBL26556 0.74 MEN1 (0.31)
SCHEMBL134811 0.72
Hydrochloric Acid SCHEMBL9616927 0.70
SCHEMBL3172913 0.70
SCHEMBL7111906 0.70
SCHEMBL2370876 0.70
SCHEMBL5088026 0.67
SCHEMBL334206 0.65 CYP3A4 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0470434-B1 Trifluoro- resp. chlorodifluoromethoxy-1,3-5-triazine and process for their preparation BASF AG (DE) 1995-10-11 EP claimed
EP-0470434-A2 Trifluoro- resp. chlorodifluoromethoxy-1,3-5-triazine and process for their preparation BASF Aktiengesellschaft (DE) 1992-02-12 EP claimed
EP-0470434-B1 Trifluoro- resp. chlorodifluoromethoxy-1,3-5-triazine and process for their preparation BASF AG (DE) 1995-10-11 EP disclosed
US-5280118-A Trifluoro-and chlorodifluoromethoxy-1,3,5-triazines BASF AKTIENGESELLSCHAFT (DE) 1994-01-18 US disclosed
US-5194610-A TRIFLUORO- AND CHLORODIFLUOROMETHOXY-1,3,5-TRIAZINES AND THE PREPARATION THEREOF BASF AKTIENGESELLSCHAFT (DE) 1993-03-16 US disclosed
EP-0470434-A2 Trifluoro- resp. chlorodifluoromethoxy-1,3-5-triazine and process for their preparation BASF Aktiengesellschaft (DE) 1992-02-12 EP disclosed