⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28785800 | 0.78 | GABRA1 (0.36) | — | |
| SCHEMBL8568961 | 0.75 | — | — | |
| SCHEMBL26556 | 0.74 | MEN1 (0.31) | — | |
| SCHEMBL5187237 | 0.74 | BDKRB2 (0.30) | — | |
| SCHEMBL134811 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL9616927 | 0.70 | — | — | |
| SCHEMBL3172913 | 0.70 | — | — | |
| SCHEMBL9185014 | 0.70 | — | — | |
| SCHEMBL7111906 | 0.70 | — | — | |
| SCHEMBL27691808 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547645-B1 | PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV | JANSSEN PHARMACEUTICALS INC (US) | 2018-07-04 | — | — | EP | claimed |
| EP-3239129-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV | Janssen Pharmaceuticals, Inc. (US) | 2017-11-01 | — | — | EP | claimed |
| US-9586893-B2 | Processes and intermediates for preparing a macrocyclic protease inhibitor of HCV | Janssen Pharmaceuticals (US) | 2017-03-07 | — | — | US | claimed |
| US-9227965-B2 | Processes and intermediates for preparing a macrocyclic protease inhibitor of HCV | Janssen Pharmaceuticals, Inc. (US) | 2016-01-05 | — | — | US | claimed |
| US-20140228574-A1 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-14 | — | — | US | claimed |
| EP-2758386-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV | Janssen Pharmaceuticals, Inc. (US) | 2014-07-30 | — | — | EP | claimed |
| WO-2013041655-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV | Janssen Pharmaceuticals, Inc. (US) | 2013-03-28 | — | — | WO | claimed |
| EP-2547645-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV | Janssen Pharmaceuticals, Inc. (US) | 2013-01-23 | — | — | EP | claimed |
| US-20130005976-A1 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV | Janssen Pharmaceuticals, Inc. (US) | 2013-01-03 | — | — | US | claimed |
| WO-2011113859-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV | ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC (US) | 2011-09-22 | — | — | WO | claimed |
| EP-4359391-B1 | TRIAZINE DERIVATIVES FOR THE TREATMENT OF TUMOURS AND NEURODEGENERATIVE DISORDERS | UNIV DEGLI STUDI MILANO (IT) | 2026-03-18 | — | — | EP | disclosed |
| US-20240327387-A1 | TRIAZINE DERIVATIVES FOR THE TREATMENT OF TUMOURS AND NEURODEGENERATIVE DISORDERS | UNIVERSITA DEGLI STUDI DI MILANO (IT) | 2024-10-03 | — | — | US | disclosed |
| EP-3604305-B1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | WAKUNAGA PHARMA CO LTD (JP) | 2024-08-28 | — | — | EP | disclosed |
| EP-4359391-A1 | TRIAZINE DERIVATIVES FOR THE TREATMENT OF TUMOURS AND NEURODEGENERATIVE DISORDERS | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2024-05-01 | — | — | EP | disclosed |
| CN-110520422-B | Novel pyridonecarboxylic acid derivative or salt thereof | 涌永制药株式会社 | 2023-09-05 | — | — | CN | disclosed |
| WO-2005042588-A1 | CELLULOSE DERIVATIVE | LENZING AKTIENGESELLSCHAFT (AT) | 2005-05-12 | — | — | WO | disclosed |
| US-4778888-A | Boron containing 1,3,5-triazines | W. R. GRACE & CO. (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0135381-B1 | REACTIVE DYES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-01-28 | — | — | EP | disclosed |
| US-4562251-A | Agarose derivatives of amino phenyl boronic acid | AMICON CORPORATION (US) | 1985-12-31 | — | — | US | disclosed |
| EP-0135381-A1 | Reactive dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-03-27 | — | — | EP | disclosed |