Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7798194 | 0.89 | HSD17B10 (0.36) | DHFRLMNATP53GAAHSD17B10 | |
| SCHEMBL7798088 | 0.86 | MPL (0.32) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL9185428 | 0.84 | HSP90AA1 (0.42) | NPC1RAB9AGMNNUSP2LMNA | |
| SCHEMBL9190088 | 0.84 | TSHR (0.35) | NPC1RAB9ALMNAALOX15SMN1; SMN2 | |
| SCHEMBL7806805 | 0.84 | MEN1 (0.34) | NPC1RAB9ALMNACYP1A2PDE4D | |
| SCHEMBL7798101 | 0.81 | CHRNA7 (0.37) | DHFRLMNATP53GAASMN1; SMN2 | |
| SCHEMBL9199934 | 0.81 | HSP90AB1 (0.48) | DHFRHSP90AA1HSP90AB1 | |
| SCHEMBL9185349 | 0.80 | — | — | |
| SCHEMBL9201644 | 0.80 | MAPT (0.38) | MAPK1 | |
| SCHEMBL7804027 | 0.80 | ALDH1A1 (0.39) | DHFRRAB9ALMNACYP1A2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469462-B1 | 2-Amino-(fluoroalkoxy-1,3,5-triazines) and method for their preparation | BASF AG (DE) | 1995-10-11 | — | — | EP | disclosed |
| US-5342939-A | 2-amino-4-fluoroalkoxy-1,3,5-triazines and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-30 | — | — | US | disclosed |
| US-5214143-A | 2-AMINO-4-FLUOROALKOXY-1,3,5-TRIAZINES AND THE PREPARATION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1993-05-25 | — | — | US | disclosed |
| EP-0469462-A1 | 2-Amino-(fluoroalkoxy-1,3,5-triazines) and method for their preparation | BASF Aktiengesellschaft (DE) | 1992-02-05 | — | — | EP | disclosed |