Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | MGMT | P16455 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197449 | 0.87 | MAPT (0.36) | MAPTMAPK1CDK1CCNB1MGMT | |
| SCHEMBL11132586 | 0.86 | MAPK1 (0.47) | MAPTMAPK1CDK1CCNB1MGMT | |
| SCHEMBL24727889 | 0.82 | MAPT (0.47) | MAPTMAPK1CDK1CCNB1MGMT | |
| SCHEMBL9185017 | 0.80 | DHFR (0.32) | MAPK1 | |
| SCHEMBL7806805 | 0.77 | MEN1 (0.34) | MAPK1 | |
| SCHEMBL23181 | 0.75 | MAPK1 (0.55) | MAPTMAPK1CDK1CCNB1MGMT | |
| SCHEMBL8874711 | 0.74 | CDK1 (0.38) | MAPTMAPK1CDK1CCNB1MGMT | |
| SCHEMBL24728017 | 0.74 | MAPT (0.41) | MAPTMAPK1CDK1CCNB1MGMT | |
| Hydrogen Sulfide SCHEMBL20395887 | 0.73 | MAPK1 (0.53) | MAPTMAPK1CDK1CCNB1MGMT | |
| SCHEMBL14585701 | 0.73 | MEN1 (0.45) | MAPTMAPK1CDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469460-B1 | Herbicidal sulphonylureas, method for their preparation and intermediates | BASF AG (DE) | 1995-10-18 | — | — | EP | disclosed |
| US-5188657-A | Herbicides consisting of sulfonyl-1,3,5-triazin-2-ylureas | BASF AKTIENGESELLSCHAFT (DE) | 1993-02-23 | — | — | US | disclosed |
| EP-0469460-A1 | Herbicidal sulphonylureas, method for their preparation and intermediates | BASF Aktiengesellschaft (DE) | 1992-02-05 | — | — | EP | disclosed |