Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088912 | 0.78 | GRIK1 (0.35) | CES2CES1GRIK1TSHR | |
| SCHEMBL11804454 | 0.75 | — | — | |
| SCHEMBL8725024 | 0.74 | CES2 (0.39) | CES2CES1MGLLHDAC8HDAC6 | |
| SCHEMBL5322702 | 0.74 | CES2 (0.39) | CES2CES1MGLLHDAC8HDAC6 | |
| SCHEMBL9639023 | 0.74 | CES2 (0.39) | CES2CES1MGLLHDAC8HDAC6 | |
| SCHEMBL15703261 | 0.74 | CES2 (0.39) | CES2CES1MGLLGRIK1HDAC8 | |
| SCHEMBL28954239 | 0.74 | CES2 (0.39) | CES2CES1MGLLGRIK1HDAC8 | |
| SCHEMBL29013577 | 0.68 | CES2 (0.46) | CES2CES1GRIK1HDAC8HDAC6 | |
| SCHEMBL7159243 | 0.67 | GRIK1 (0.44) | CES2CES1GRIK1HDAC8HDAC6 | |
| SCHEMBL5333680 | 0.67 | GRIK1 (0.44) | CES2CES1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426142-B1 | Method of making ring-opened polynorbornene polymers using pot life extending agents | NIPPON ZEON CO (JP) | 1995-09-20 | — | — | EP | claimed |