Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11804454 | 0.97 | — | — | |
| SCHEMBL7636797 | 0.83 | — | — | |
| SCHEMBL9185124 | 0.78 | CES2 (0.36) | GRIK1CES2CES1TSHR | |
| SCHEMBL5333680 | 0.75 | GRIK1 (0.44) | GRIK1GRIK2CES2CES1 | |
| SCHEMBL11806189 | 0.73 | GRIK1 (0.34) | GRIK1GRIK2 | |
| SCHEMBL607401 | 0.73 | TSHR (0.35) | GRIK1GRIK2TSHR | |
| SCHEMBL6058418 | 0.73 | GRIK1 (0.34) | GRIK1GRIK2 | |
| SCHEMBL9682187 | 0.71 | GRIK1 (0.37) | GRIK1GRIK2 | |
| SCHEMBL9682196 | 0.71 | GRIK1 (0.37) | GRIK1GRIK2 | |
| SCHEMBL28954239 | 0.71 | CES2 (0.39) | GRIK1GRIK2CES2CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008015714-A2 | PROCESS FOR THE PREPARATION OF 1,1-DICHLORO-2-ALKYLETHYLENE | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2008-02-07 | — | — | WO | disclosed |
| US-6359164-B1 | FROM ALDEHYDE AND TRI(CHLORO OR BROMO)ACETIC ACID IN PRESENS EOF BASIC CATALYST | DUPONT PHARMACEUTICALS COMPANY | 2002-03-19 | — | — | US | disclosed |
| WO-2000018706-A1 | PROCESS FOR THE PREPARATION OF CYCLOPROPYLACETYLENE | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-04-06 | — | — | WO | disclosed |
| US-5119221-A | Containing polymer adjustment layer | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| EP-0351718-A1 | Liquid crystal display device comprising improved alignment layers for liquid crystal | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1990-01-24 | — | — | EP | disclosed |
| US-3956411-A | DICHLOROALKYLENE | PHILLIPS PETROLEUM COMPANY (US) | 1976-05-11 | — | — | US | disclosed |