Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185815 | 0.98 | GSR (0.56) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL9179928 | 0.93 | GAA (0.58) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL3952172 | 0.93 | GAA (0.58) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL9182795 | 0.93 | GSR (0.61) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL9184605 | 0.88 | GAA (0.60) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL9179922 | 0.86 | GSR (0.73) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL9180095 | 0.85 | GSR (0.71) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL9183790 | 0.85 | GSR (0.71) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL31169456 | 0.84 | GSR (0.75) | GSRGAAKMT2AALDH1A1TSHR | |
| SCHEMBL18193748 | 0.81 | ALDH1A1 (0.57) | GSRGAAKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495450-B1 | Polyamine phenols as radioprotective agents | MERRELL DOW PHARMA (US) | 1995-07-26 | — | — | EP | disclosed |
| US-5354782-A | Polyamine phenols as radioprotective agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-11 | — | — | US | disclosed |
| EP-0495450-A2 | Polyamine phenols as radioprotective agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-22 | — | — | EP | disclosed |